Suppression of body fat accumulation in myostatin-deficient mice

Suppression of body fat accumulation in myostatin-deficient mice.

Myostatin is a TGF-beta family member that acts as a negative regulator of muscle growth. Mice lacking the myostatin gene (Mstn) have a widespread increase in skeletal muscle mass resulting from a combination of muscle fiber hypertrophy and hyperplasia. Here we show that Mstn-null mice have a significant reduction in fat accumulation with increasing age compared with wild-type littermates, even...

Body Fat Accumulation inPromotes Mice

major pungent component in fruits of CZTpsium, has been reported to increase the catecholamine secretioni) and energy expenditure2) and suppress body fat accumulation by long-term treatment3} in experimental animal studies. Although hot peppers and capsaicin may be used in a diet therapy for obesity, their usage as a food additive or a drug is limited by its strong pungency and nociceptive acti...

Increased energy expenditure and leptin sensitivity account for low fat mass in myostatin-deficient mice.

Myostatin deficiency causes dramatically increased skeletal muscle mass and reduced fat mass. Previously, myostatin-deficient mice were reported to have unexpectedly low total energy expenditure (EE) after normalizing to body mass, and thus, a metabolic cause for low fat mass was discounted. To clarify how myostatin deficiency affects the control of body fat mass and energy balance, we compared...

evaluation of fat atrophy in patients with dermis fat graft of orbit by ct-scan

چکیده ندارد.

Mandibular Shape in Myostatin-deficient Mice: a Geometric Morphometric Analysis